Colchicine Side Effects

Colchicine side effects can prevent this gout medicine being used for pain relief.

Investigations leading to 2010 licensing of colchicine as Colcrys in the USA, have shown that some side-effects are due to the way colchicine has been prescribed in the past. Specifically, those gout studies found that the dose of colchicine was too high in many cases.

This colchicine side effects page covers:

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Best Tophi Picture

I think this is the best tophi picture. Because it shows successful tophi treatment. Most tophi photographs are horrible. But I think you should know the dangers of untreated gout.

Despite the advances in science that mean we can now control gout, there is a tiny minority who cannot tolerate common uric acid-lowering treatment. If you do not get uric acid to safe concentration, you are doomed to the continuous growth of tophi. So, you might treat the pain, but can you control the gout?

Pain relief without uric acid control means more and more uric acid crystals that will eventually show themselves as gouty tophi.

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Allopurinol For Gout

My allopurinol for gout guidelines explain some implications of taking allopurinol for gout.

The main reason for taking allopurinol is to lower uric acid. When it is prescribed correctly, your doctor will take regular blood tests to ensure that your uric acid stays below 6mg/dL. In most cases, the upper limit should be 5mg/dL. For the early months of allopurinol, which is often referred to as the “debulking period,” your target should be much lower than 5mg/dL.

Those are the basic facts about allopurinol for gout. I explain those facts, and others, in detail throughout these allopurinol guidelines. In this page, I look at some practical issues that show why you have to be vigilant about your uric acid level, and your allopurinol dosage.

Despite a half century of allopurinol as the first choice treatment for gout, correct prescribing remains inadequate. In recent years, professional rheumatologists throughout the world have emphasized the need to set safe uric acid levels on a personal basis. Thereafter, physicians should treat-to-target. That is, every gout patient should have a personal target uric acid level, and allopurinol dose should be adjusted to meet that target. In addition, gout patients should:

  • Be pre-screened for genetic liability to Allopurinol Hypersensitivity Syndrome in at-risk ethnic groups (Korean, Han Chinese, and Thai). See Minimize Allopurinol Side Effects
  • Know about the risks of gout flares during the debulking period.
  • Have access to pain prevention or pain treatment during the debulking period.
  • Have kidney function and liver function tests alongside uric acid tests.
  • Have adequate follow-up care for life

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The Gout & Colchicine Dosage Facts

The Gout & Colchicine Dosage Facts are answers to questions about colchicine dose. So, they help answer questions such as how should you take colchicine, and when should you stop, etc.

The complete facts about colchicine are in the Colchicine guidelines. But here is a selection of questions commonly asked in the gout forums. Please remember that these are only a quick guide to general dosage aspects of colchicine. If you are in doubt, you should ask your doctor.

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Anti-Inflammatory Gout Cure Brings Pain Relief

The gout cure you look for first is one that will relieve the agony.

Though it is vital, in the long term, to control uric acid, those treatments will not give the immediate gout pain relief that you need.

Gout Cure List
Colchicine
Ibuprofen
Indomethacin

Whilst you wait for your uric acid treatment to get you to safe levels, you can look to the pain relieving treatments listed here.

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Is Gout Massage A Bad Treatment Of Gout?

One of the most popular gout topics is massage and gout.

It started with a forum member asking:

A couple times I have massaged the toe joint and it felt like perhaps I was able to break up the crystals a bit. Not sure if that can really happen or if I imagined it. So, my questions are: 1) can you really break down the crystals by manually massaging the joint? 2) if so, should you? Would that help break it down and assist in the process? Or, is it doing more harm than good?

Inevitably, as forum discussions tend to do, there is talk of supporting the gout massage with hot baths, which in turn leads to a discussion of what to put in the bathwater. But this misses the fundamental question: is massage good gout relief, or will massaging gout cause more problems?
Click to discover the dangers of misunderstanding gout and massage

Relief From Stubborn Gout Pain

In my gout pain relief pages, I explain the best approach to gout pain.

The main difficulty with stubborn gout pain is, it rarely responds to a simple treatment. Usually, you need a combination of more than one pain-relieving drug. Often these combinations need to include general painkillers that are not specifically for gout.

Recently, I was asked about combining indomethacin with colchicine for relieving stubborn gout pain.

There are thousands of different combinations that work.

The secret is finding the right combination that suits you.

Colchicine For Stubborn Gout Pain Relief

Gout pain, as I explain in the Uric Acid guidelines, is a result of the immune reaction to invading uric acid crystals. When the immune system becomes overwhelmed, it calls in reinforcements, and this process is at the heart of the agony we experience during an acute gout flare.

Colchicine, sold as Colcrys in America, is very effective when it is taken early enough. That is why doctors advise you to take it at the first sign of a gout flare. The main purpose of colchicine is to prevent, or limit, gout flares when you take uric acid lowering gout medications.

Colchicine works to prevent gout pain, or prevent it getting worse, by slowing your immune system. White blood cells are restricted from growing, and this limits the inflammation that is part of that process.
See why you may need more than colchicine for stubborn gout pain