Uric Acid Category

Uric Acid Info section (Understand Gout). This section explains what uric acid is, and how it causes gout. By giving you the information you need to understand uric acid, you are best placed to manage it effectively.

Lowering Uric Acid: What Are The Pitfalls?

We know that lowering uric acid is the only way to remove the risk of more gout attacks and joint damage. We know that, once a gout attack has occurred, we must keep uric acid at, or below, 5mg/dL. We know that uric acid crystal deposits will dissolve faster at lower uric acid levels.

How Does Lowering Uric Acid Cause More Gout Attacks?

Many people who start taking uric acid lowering treatments are surprised to see gout attacks increasing.

They feel pain in many joints, and often in joints that haven’t had problems before.

Good doctors will prescribe pain relief for the first few months of treatment for lowering uric acid, but why do we need this?

Many years ago, I learned that dissolving uric acid crystals are just as likely to cause gout as newly formed crystals. This prompted me to publish Allopurinol Medication: Why It Hurts To Get Rid Of Gout, which is the cornerstone of my approach to fixing gout. Though the article features allopurinol, the process applies to any method for lowering uric acid. There are now newer medical options besides allopurinol and probenecid, and the process also applies to lifestyle improvements that reduce uric acid. It is central to my view that you cannot manage a gout diet by tracking foods that trigger gout attacks, because you cannot tell if the attack is caused by new crystals forming, or old ones dissolving.
Learn how to overcome the pitfalls of lowering uric acid

Hyperuricemia – Excess Uric Acid

Hyperuricemia means elevated uric acid. Everyone knows that excess uric acid causes gout.

But is it that simple?
No, there are many issues.

Where does uric acid come from?
You can’t buy it. Your body produces it by breaking down proteins. If you have too much, you’ve got hyperuricemia. I’ve covered 4 main reasons for excess uric acid below.
How much is too much?
No fixed level is right or wrong. 3-7 mg/dl is average. Some people have higher levels and no gout. If you have gout, you need to keep the level below 6 mg/dl.
How can I control it?
Managing uric acid levels is never easy, but there are several treatments that help. Understanding why you have a problem is the first step to solving it. Follow the guidance here and throughout my website to find ways to control uric acid that suit you.

Continue reading Hyperuricemia – Excess Uric Acid

Uric Acid Crystal Pictures

Uric Acid

Each uric acid crystal is microscopic.

You never get to see them, let alone watch them get beaten.

Now you can.

EULAR (EUropean League Against Rheumatism) has produced 6 still images of a uric acid crystal meeting a white blood cell.

I used 4 of these pictures in the image showing on the right. See a full size version of my uric acid crystal graphic below

You can see more images below, but first let me explain some very important points revealed by these pictures.

Continue reading Uric Acid Crystals Pictures

Uric Acid Management

We know that uric acid causes gout, and we’ve seen that diet can minimize overproduction and under-secretion.

As well as diet, another approach is to look at directly reducing the level in your blood using drugs or dietary supplements.

Once again, there is a great deal of information about various substances that can reduce uric acid levels in the blood, and once again there is no simple solution.
Products and potions that work perfectly well for one person can often have no effect, or adverse effects on another.
You should also bear in mind that some substances can increase levels – commonly diuretics and low doses of aspirin.

Continue reading about Uric Acid Management

Reduce Uric Acid – Get Rid Of Gout

Reduce Uric Acid

Your top concern must be how to reduce uric acid.

Gout sufferers are obviously concerned with pain and food, but the most important thing you must learn is how to lower the uric acid.

If you can manage uric acid, you can manage your gout.

If you do not manage uric acid you will never get rid of gout. Whatever treatment you are taking for gout, medical or alternative, you must measure uric acid levels.

Arrange for regular blood tests to test uric acid. It is the only way to tell if treatment is working or not. Do not rely on the fact that pain may have gone. If uric acid is not lower than 6mg/dL (0.36mmol/L) then your gout pain will come back – probably worse than ever.

Gout Information

I have written several pages about uric acid, including how to lower uric acid levels and how to avoid raising them.

It is a complicated subject, particularly as uric acid is a good thing. It is vital for humans, but too much of it can lead to gout.

Each month I review which are the most popular pages on my website. This month, two pages about uric acid made the top three. This does not surprise me, as most gout sufferers are looking for more information about uric acid and how to reduce it.

2011 Update

I moved this Reduce Uric Acid (first published in May 2008) page here as part of the ongoing website upgrade. The popular pages refer to an old method I had for highlighting the best pages. This is now replaced by the section on the menu called “Best Gout & Uric Acid Pages”. Currently, the pages in that list change daily, but continue to feature pages about lowering uric acid.

You can learn more about how to reduce uric acid in the Reduce Uric Acid with Allopurinol pages, which cover all aspects of lowering uric acid with allopurinol.

What Gout Is – Simple Explanations from a Simple Mind

This page about what gout is, is the Explanations section from the old style website. It is now maintained in the Understanding Uric Acid section where I explain all the principles of uric acid, hyperuricemia and gout.

I Need to Know What Gout Is

What Gout Is

People affected by painful, swollen joints want to know what gout is. Sufferers and their carers are often confused by almost every aspect of gout, also called gouty arthritis.

My Explanations Of What Gout Is

When I started this website in February 2005, I was totally confused by gout.As I’ve researched different aspects of gout I’ve learned more, but I’m still learning. I will keep researching, reporting and explaining until a cure for gout is found.

Month by month, I’m growing the amount of information and looking for new ways to present it so that you can easily find and understand what you need.

What Gout Is

The hardest task, for me, was to understand what gout is. It may seem obvious, but even the medical profession have difficulty in an absolute definition. From a personal point of view, it probably doesn’t matter what gout is. If there were a standard reliable cure, it would matter even less.

But there is no magic cure, so the best approach is to understand what happens in your body to cause pain. I’ve learned that this is an extremely complex series of bio-chemical processes. Some are easy to understand, others less so. The complexity leads to confusion. Confusion leads to doubt. Managing gout in this situation is extremely difficult, if not impossible.

To try and cut through this cloud of confusion and doubt I have developed an explanation of what gout is. This explanation of how gout pain is caused is at the heart of making the best personal choice of treatments that suit you.

Clouds of Gout

What Gout Is - Clouds of Gout

Many advisers say that uric acid crystals resulting from excess uric acid in the blood cause gout pain. The standard solution is to:

  1. Treat the pain with appropriate anti-inflammatory drugs.
  2. Reduce uric acid levels by with a low purine diet or daily medication to remove uric acid from the blood.

This approach works for many people, but it is no use for those, like me, who want a fuller dietary choice and do not want to take lifelong daily medication. I accept that some restrictions may be necessary, but I know that these are available through small changes in lifestyle – not wholesale misery!

I also accept that I need a simple view of what gout is when I plan and implement those lifestyle changes. Now that I clearly see that U-D-R-P leads to gout pain, I can more easily manage my gout. Small lifestyle changes based on beating U-D-R-P let me reduce the intensity and frequency of gout pain, and let me deal with that pain in a more positive manner.

I have added the Clouds Of Gout graphic to some pages to show what part of gout they are about, and a link to an explanation of that part of gout. If you spot any pages that I have missed, please let me know.

For a fuller explanation of what gout is, see uric acid causes gout pain.


Why Do The Best Gout Cures Hurt?

Now that you understand what gout is, it’s easier to understand why curing gout can hurt. I’ve written this article on allopurinol medication to explain why. Please note that it actually applies to all gout treatments that lower uric acid, not just allopurinol.


Gout Food Ratings


PRAL

PRAL stands for Potential Renal Acid Load. It is a simple calculation to estimate the expected acid inducing compounds from digested foods.

Studies have shown PRAL to be a reliable indication of the acidifying or alkalizing effect of food.

Positive values have a pH lowering, acid effect. Negative values have a pH raising, alkaline effect. It is important to include both acid and alkaline foods in your diet to gain a range of nutrients, with an overall total in the alkaline range. Opinions vary, but the best ratio of alkaline:acid foods is about 67:33 up to 80:20

Read more at my PRAL and alkaline foods introduction.


Antioxidant Rating

Antioxidants are good for health according to many experts. I only know of one study that shows antioxidants reduce uric acid – tell me if you find others.

There are many different antioxidants, and different ways to measure them. Until we know more about how specific antioxidants affect different aspects of health, I am highlighting those with high total antioxidant capacity as being best gout diet choices.

To avoid assigning absolute numbers to foods that can vary widely according to season, variety, growing conditions and cooking methods, I have assigned an antioxidant rating. These are High, Medium, Low, Negligible and Unknown. Even low antioxidant foods are good for you, especially where they add variety to a diet that already includes plenty of antioxidants.

I no longer maintain Gout Food Analysis pages, therefore the antioxidant rating, and the following ratings, no longer apply. See the Gout Diet section for guidance on how to plan and maintain an effective diet for gout.

Inflammation Factor

Inflammation factor is a proprietary formula for assessing the inflammatory, or anti-inflammatory effects of food. The higher the number, the more anti-inflammatory the food is.

Inflammation factor takes account of the different effects of different nutrients. High-antioxidant foods will often show a high Inflammation Factor, but the values may be reduced when foods contain high carbohydrates, particularly sugars, which have an inflammatory effect.

In the absence of scientific evidence to show the effects on gout, I am relying on commonsense to judge that anti-inflammatory foods must be good for gout.

As with acid/alkaline foods, it is important to eat a range of inflammatory and anti-inflammatory foods, but the total daily value should be positive, i.e. anti-inflammatory. A daily total of around 200 is a good target for gout sufferers.

Fullness Factor

Many weight loss plans focus on calories, but if you fill your calorie allowance from foods that do not satisfy your appetite, you will always fight a losing battle against weight. The Fullness Factor is a proprietary rating system that gives a higher rank to foods that are more filling. The rating ranges from 0 to 5, with 5 being the best.

If you are overweight, you can lose weight on the GoutPal Diet by gradually exchanging foods that do not satisfy your hunger, for those that do.

Nutrition Rating

The Nutrition Rating is a proprietary method for ranking foods according to the amount of nutrients per calorie. The rating ranges from 0 to 5, with 5 being the best.

What About Purines?

I have not included purines in the gout food ratings as I do not think they are relevant to what gout is. A few studies have shown that high purine foods can increase uric acid, but the ones I have seen are based on extreme diets or non-humans. Many extreme diets will raise uric acid, as will starvation. Your body battles against poor nutrition to neutralize oxidizing foods. Often, body tissue breaks down, producing excess uric acid, as cells die. Every fact I have read about leads me to the conclusion that you will produce more uric acid as a result of poor diet than you will ever get from a plateful of even the highest purine food.

I have retained the table of high purine foods for those people who believe that purines in food affect gout.

Uric Acid Causes Gout Pain

This is my original explanation of how uric acid causes gout pain, from some time before 2008. It exposes the commonly believed myth that gout pain comes from sharp uric acid crystals embedded in our joints. In truth, gout pain comes from our inflammatory reaction to these crystals, which are too small to cause physical pain. This simple misunderstanding causes all kinds of problems during diagnosis and treatment.

GoutPal.com has grown considerably since I first published this explanation on the causes of gout pain, yet this simple process continues to support everything that I do here. The U-D-R-P process has now spawned an entire section (Understanding Uric Acid) to explain how uric acid and gout interact with our immune system to produce gout.

My Symptoms, Treatment, Diet Sections offer practical help and advice for coping with gout, but understanding uric acid gives you a much better chance of managing gout completely. If you do not have time to read all the Understanding Uric Acid Section, at least take time to read and understand the principles upon which it is based… (more…)

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