Is Allopurinol A Lifetime Drug? » Allopurinol: 5 Years – Not Life

Title:
Using serum urate levels to determine the period free of gouty symptoms after withdrawal of long-term urate-lowering therapy: a prospective study.
Authors:
Perez-Ruiz F, Atxotegi J, Hernando I, Calabozo M, Nolla JM. Arthritis Rheum.
Published:
2006 Oct 15;55(5):786-90.

Definitive study on long term allopurinol usage. It confirms that, whilst uric acid testing once or twice a year (“twice during the first year [after ULT withdrawal] and at least once a year thereafter”) is a lifetime commitment, allopurinol administration is best limited to 5 years at a time.

Allopurinol: 5 Years - Not Life
allopurinol-5-years-not-life.pdf

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