Gouty Arthritis Related Section

Gout articles that do not fit into the main gout help sections, including features about the GoutPal.com website.

Any Hope For Gout When It’s Gone Too Far?

All too often, gout management is focused too much on pain relief, with too little emphasis on uric acid management.

Failure to correct high concentrations of uric acid, which is the root of all gout pain, leads to damage to joints (osteoarthritis). This in turn, leads to the question, “Can anything be done to help repair gout-damaged joints?”

More specifically a reader asked:

Was wondering if anyone had some info on glucosamine supplements in regard to helping to heal the damage done by years of gout.

Well, there is information available, but the results are not encouraging. Though the British Medical Journal has had responses to the following report that raise some questions about the conclusions, the hope of joint repair through supplementation does seem very doubtful. In “Effects of glucosamine, chondroitin, or placebo in patients with osteoarthritis of hip or knee: network meta-analysis,” (Glucosamine Or Chondroitin For Damaged Joints) Warner & colleagues conclude:

Compared with placebo, glucosamine, chondroitin, and their combination do not reduce joint pain or have an impact on narrowing of joint space. Health authorities and health insurers should not cover the costs of these preparations, and new prescriptions to patients who have not received treatment should be discouraged.

They also note that:

Our findings indicate that glucosamine, chondroitin, and their combination do not result in a relevant reduction of joint pain nor affect joint space narrowing compared with placebo. Some patients, however, are convinced that these preparations are beneficial, which might be because of the natural course of osteoarthritis, regression to the mean, or the placebo effect. We are confident that neither of the preparations is dangerous. Therefore, we see no harm in having patients continue these preparations as long as they perceive a benefit and cover the costs of treatment themselves. Coverage of costs by health authorities or health insurers for these preparations and novel prescriptions to patients who have not received other treatments should be discouraged.

I do not know if there are other effective treatments once gout has caused osteoarthritis, but commonsense dictates that you should see your doctor immediately about uric acid lowering gout medications before permanent joint damage occurs.

Uric Acid Arthritis – A Better Name For Gout

Uric Acid Arthritis

If we called gout uric acid arthritis would we get better treatment?

Gout is an old-fashioned word.

Through the ages it has been associated with pain, which is true.

It has also been associated with excessive luxurious living – the “rich man’s disease,” or “disease of kings,” which is less true.

Gout has long been known as a build up of uric acid. This leads to uric acid being deposited in and around the joints as mono sodium urate (MSU) crystals. Hence, gout’s other name – crystal arthritis, or crystal-induced arthritis.

Though gout is medically recognized as a type of arthritis, it’s common perception that it is self-inflicted through high living prevails. This misconception follows, at least partially into the medical profession. How many doctors prescribe a few unmonitored pills and offer dietary advice yet fail to provide a proper uric acid management program? Quite a few judging by my postbag.

Of course, if you start talking about uric acid arthritis, people may not understand you. But you can start thinking of it in this way. Start to concentrate on uric acid and how to manage it, then the gout will take care of itself.

This Uric Acid Arthritis page, first published before May 2008, is republished here as part of ongoing website maintenance.

Gout Help

The gout help on this site, and at GoutPal Interactive, helps hundreds of gout sufferers every year.

It’s a pleasure to provide this gout support service, though I’m often asked what people can do for me in return.

The greatest thanks that I receive is when someone learns useful gout information here, then uses it to help another gout sufferer in the gout forum, or elsewhere. I’m particularly grateful if that includes a link back to relevant pages on this website.

Close to that are the great questions. Those help me improve this website, as do suggestions for improving this website. I wish it to be a comprehensive source of information and practical tips to let all gout sufferers find their Gout Freedom. I can only do that with your feedback.

Beyond those lofty ambitions, there is always the subject of money. Yes, this gout support service does require money to run. That is why I include adverts, product commissions, and sponsored search. I would like your feedback on services that you have found useful, in order that I might improve this area – adding new recommended gout products and services, or removing unsatisfactory ones.

I have suspended the donation feature due to problems with the service provider (or rather lack of service), PayPal. If you feel you would like to reward me, please see my Help For Gout page, but I would much rather you thank me by helping me improve this website, and helping other gout sufferers with your newfound experience.

Increased Uric Acid

Increased Uric Acid – Increased Death Risk

Doctors have suspected links between increased uric acid and increased risk of heart problems for over 100 years.

After decades of ignoring these risks, several investigations show links between high uric acid & heart disease, including higher risks of death.

Though these links are becoming clearer every year, there is little evidence that there are any improvements in treatment. Let’s look at the risks, and ways you can improve your chances of avoiding death from increased uric acid.

Heart Risks Associated With Increased Uric Acid

Current thinking is neatly encapsulated in last year’s review by Gagliardi and colleagues [1]. Uric acid: A marker of increased cardiovascular risk, starts by telling us that uric acid has been linked with heart disease since the 19th century. At that time, there was no easy way to lower uric acid, though we now have effective gout treatments to avoid risks of high uric acid.

Over one hundred years later, we have a wealth of uric acid research relating to heart and associated risks. So common, that the review refers to “classical association of gout, hypertension, obesity and cardiovascular disease” [my bold]. It points out that, in addition to the well-known relationship between uric acid and deficiencies in purine metabolism, “increased uric acid is generally associated with important risk factors for atherosclerosis like hypertension, abdominal obesity, insulin resistance, the metabolic syndrome and renal failure.”

All these associations between uric acid and heart disease risks are reported in detail by Feig and colleagues [2].

More specifically, Car & Trkulja [3] have investigated uric acid levels in patients admitted to hospital with heart attacks. They have shown that increased uric acid is associated with increased risk of death in hospital, and death within 30 days. It is also associated with lower survival rates over five years following the heart attack.

Increased Uric Acid Conclusions

All these studies emphasize that whilst higher uric acid is associated with higher heart disease risks, nobody knows if there is any causal link. Neither do they show if heart disease problems are decreased if uric acid levels are decreased.

Although we do not know if increased uric acid might cause heart problems, or if undiagnosed heart problems cause high uric acid, several studies have shown that the risks are linked.

Increased Uric Acid Next Steps

If you have a personal or family history of high uric acid, it is important to see your doctor about your risks of heart disease.
Similarly if you have a personal or family history of heart disease, it is important to see your doctor about checking your uric acid level.

Leave Increased Uric Acid to browse the Gout Disease pages


Increased Uric Acid References

  1. Authors: Gagliardi AC, Miname MH, Santos RD. Title: Uric acid: A marker of increased cardiovascular risk. Published: Atherosclerosis. 2009 Jan;202(1):11-7.
  2. Authors: Daniel I. Feig, M.D., Ph.D., Duk-Hee Kang, M.D., and Richard J. Johnson, M.D. Title: Uric Acid and Cardiovascular Risk. Published: N Engl J Med. 2008 October 23; 359(17): 1811–1821. Uric Acid And Heart Risks
  3. Authors: Car S, Trkulja V. Title: Higher serum uric acid on admission is associated with higher short-term mortality and poorer long-term survival after myocardial infarction: retrospective prognostic study. Published: Croat Med J. 2009 Dec;50(6):559-66. Uric Acid And Heart Attack Deaths

High Uric Acid And Kidney Disease

A new report studying high uric acid and kidney disease confirms earlier indications of the dangers of hyperuricemia revealed by the 2008 Austrian investigations.

High Uric Acid & Kidney Disease Image

In a study investigating the “Association between serum uric acid and early kidney damage in middle-aged and elderly”, Chinese scientists show a clear correlation between high uric acid in the blood and reduced kidney function.

Though this new report[1] adds nothing to the Austrian study[2] in terms of understanding why elevated uric acid leads to kidney impairment, it does confirm that the two are linked. It certainly adds weight to my position that asymptomatic hyperuricemia should be taken much more seriously.
Learn more about High Uric Acid And Kidney Disease

2010 Gout Blog

The Fast, Full & Fresh Gout Blog

GoutPal’s 2010 gout blog celebrates 5 years of gouty arthritis help, advice and news.

Your Gout Blog

GoutPal will help with your gout diet, give advice about gouty symptoms, and tell you about new treatments for uric acid problems.

This blog is your place for gout news. Not just the latest gout treatment and remedies news, but all new information that affects gout sufferers and their carers. It includes:

  • New ways to get gout help
  • New information to understand gout
  • New guidelines distilling the ever-increasing knowledge-base built by the GoutPal community.

This blog introduces you to new information in key gout sections:

(more…)

Free Gout Guides

You need free gout guides to help you understand your doctor’s advice.

They help you know what questions to ask.

You even feel a little bit better just because you understand gout better.

Even if you do not suffer from any other poor health condition, gout alone is hard to understand. Though the experts call this “uncomplicated gout”, it is far from simple. If you have other conditions as well, such as high blood pressure (hypertension), kidney problems (renal insufficiency), or heart problems (cardio-vascular disease), then you are in a place that even qualified professionals find hard.

So how can free gout guides from a layman help?

I am a fellow gout sufferer with an addiction to finding out as much as I can about gout. Unlike most doctors, I have felt the fierce stabbing pain of gout. I have felt the frustration of not understanding gout advice.

Continue reading about Free Gout Guides

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