Resveratrol Xanthine Oxidase Inhibitor Investigation

This investigation into resveratrol as one of natures gout cures includes the following:

We have investigated the free radical scavenging capacity of resveratrol, its effects on xanthine oxidase (XO) activity, spontaneous membrane lipid oxidation, and DNA cleavage. Resveratrol showed a dose-dependent free radical scavenging activity, significant inhibition of XO activity…

Xanthine Oxidase (xanthine: oxygen oxidoreductase, E C Activity Inhibition

Xanthine oxidase (XO) activity was evaluated spectrophotometrically by following the formation of uric acid … Different concentrations of resveratrol (50, 100, or 200 ?M) were added to samples before enzyme addition and their effect on the generation of uric acid was used to calculate regression lines.

First 2 pages are shown as an image, full report is:

Resveratrol Xanthine Oxidase Inhibitor Investigation

Antioxidant Activity and Protective Effect on DNA Cleavage of Resveratrol.
R. Acquaviva, A. Russo, A. Campisi, V. Sorrenti, C. Di Giacomo, M.L. Barcellona, M. Avitabile, A. Vanella.
Journal of Food Science Volume 67, Issue 1, pages 137–141, January 2002

Note that I refer to Xanthine Oxidase Inhibitors (XOIs) as Uric Acid Blockers.

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