Uricase Converts Uric Acid image

Uricase Converts Uric Acid image is my featured image for Uricase.

Uricase Converts Uric Acid image details

This image is from “Recent developments in our understanding of the renal basis of hyperuricemia and the development of novel antihyperuricemic therapeutics” with the caption:

Action of uricase to catabolize uric acid to allantoin. Uricase (urate oxidase) gene expression and the depicted uricase reaction are lacking in humans, as discussed in the text. PEGylated recombinant uricase preparations are now under investigation for treatment of refractory hyperuricemia in gout, and have the potential to rapidly reduce (“de-bulk”) tophus burden.

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