Uric Acid Crystals Meet White Blood Cells

This fascinating look at white blood cells in action against uric acid crystals goes a long way to explaining the agony of gout. The fragmentation of white blood cells as they fight urate crystals attracts more white blood cells to join the battle leading to a vicious circle of inflammation causing yet more inflammation.

The title, in layman’s terms, means “Looking at inflammation from uric acid crystals with large white blood cells”

Observations on phagocytosis of urate crystals by polymorphonuclear leucocytes.
Rajan KT.
Ann Rheum Dis. 1975 Feb;34(1):54-61.

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