Keith’s GoutPal Story 2020 Forums Please Help My Gout! Gout Treatment Allopurinol and dehydration question

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    I think I know the answer to this, but wanted to ask anyways.   If you are taking this drug (UA levels are where they need to be) and you work out at the gym extensively or go to the beach or lay out in the hot sun, whatever it may be that could dehydrate your body, do you risk having a gout attack?  I would say no…UNLESS this happened often, then you “might” risk kidney issues for not having enough fluids with the drug.  Any thoughts?


    If you are taking alllopurinol to achieve a level around 5., I think there is very little chance of dehydrating yopurself to the point of precipitaion.

    In fact on a hot beach, the solublility of UA is apt to be high everywhere on your body. After all, where do we get hoter tootsies than running on a blazing beach.

    Maybe drinking half a case of beer might increase the odds a bit though.


    There is a very slight risk of kidney stones with allopurinol and dehydration, due to precipitation of xanthine, oxypurinol and hypoxanthine. All the reports I've seen cite other health issues besides gout, and high allopurinol doses (e.g. 600mg per day).

    In normal cases, I would say the risk is very low indeed.

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