Keith’s GoutPal Story 2020 Forums Please Help My Gout! Gout Treatment Allapurinal and muscle twitches

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  • #3087

    Hello folks,

    I have suffered gout since college and am now 45.  After eating ibuprofin at every meal, I finally went on 300 mg allopurinol.  My gout attackes have subsided significantly. However, now I am starting to notice muscle twitches in my eye and lip 🙁   Anyone else experienced the same?


    No direct experience, but I feel that when you have given your body a big change like this, strange sensations and twitches are not unusual.

    The most important thing you can do is focus on your uric acid levels for a few months. Make sure that within a month of starting allopurinol you are way below 6mg/dL, and keep it there for at least 6 months. This will help clear all the old crystals.

    If you are still having twitches after a few weeks, it merits further investigation, but don’t let it distract you from controlling your uric acid numbers.



     I don't think it's much of anything. THese facial tics usually are casued by some pressure on a facial nerve that passes through some tortuous canals around the ear. It usually passes by itself and is almost certainly not associalted with allopurinol.

    Perhaps you have/had some small tophus around this nerve.

    If it continues for weeks orr months, go see a neurologist and see if he can isolate the problem.

    Do you feel any numbness on any spots on your face when you touch with your fingers? See if massanging any spots around your ear helps.

    Glad to hear that your allopurinol 300 is doing the job. It's a lot easier on the intestines than eating colchicine on a daily basis.

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