Tophi Removal Without Surgery

These photographs show tophi removal without surgery.

Tophi are deposits of uric acid crystals that grow under the skin. Though they are a warning sign of gout, they can appear before patients experience typical gout joint pains. Then, they will eventually grow through the skin, with associated pain and risk of infection. Also, left untreated, they will spread to other tissues, causing organ damage including kidney or heart failure.

But, you can use drugs for tophi removal without surgery. In that way, you avoid risks associated with surgery. Also, you dissolve invisible uric acid crystals hidden in joints, etc. So, with the right uric acid lowering treatment, complete gout removal is a few months away.

I’ve selected this as my best tophi picture. Because it shows how tophi can be removed without surgery if uric acid can be reduced to very low levels.

Tophi Removal Photograph Details

These two photographs are before and after images from a gout patient who received five infusions of Krystexxa (a brand name for pegloticase). 5 infusions of 8mg every 3 weeks mean this gout sufferer experienced almost complete tophi removal in 3½ months.

The photographs are from Treating gout with pegloticase, a gout study from M S Hershfield and colleagues, in 2010[1].

Pegloticase infusion rapidly lowered mean PUA [Plasma Uric Acid] to [less than] 1mg/dL in all patients, and PUA remained low in 16 of 21 patients who completed treatment.

Though Krystexxa is only normally available for patients who cannot tolerate allopurinol or Uloric (febuxostat), maximum doses of these frontline gout treatments should achieve similar results, though it may take longer.

If you want to achieve tophi removal without surgery, modern uric acid lowering drugs are your best option. They only work if you get uric acid down to 5mg/dL, but if you can go lower, tophi will resolve faster.

Get treatment for gout to remove tophi before your hands look like this!


Tophi Removal Without Surgery References

  1. Hershfield, Michael S., et al. “Treating gout with pegloticase, a PEGylated urate oxidase, provides insight into the importance of uric acid as an antioxidant in vivo.” Proceedings of the National Academy of Sciences 107.32 (2010): 14351-14356. GoutPal Members might download from Gouty Tophi Removed in 15 weeks with Pegloticase.
Please Like GoutPal on Facebook
Please Share This Page

What do you think about this page?

Did this page help you? If yes, please consider a small donation. Your donations help keep GoutPal's gout support services free for everyone. Please click to donate:

If not, please tell me how I can improve it to help you more.

Please note that my Feedback Form does not yet work on the current version of this website. So please send your feedback:

Medical Disclaimer: The pupose of GoutPal is to provide jargon-free explanations of medical gout-related terms and procedures. Because gout sufferers need to know what questions to ask their doctor. Also, you need to understand what your doctor tells you. So this website explains gout science. But it is definitely NOT a substitute for medical advice.

Information on this website is provided by a fellow gout sufferer (Keith Taylor) with an accountant's precision for accurate data. But no medical qualifications. So you must seek professional medical advice about gout and any other health matters.

Google Gout

Type your question, or gout topic, in the search box. Or see Better Desktop Gout Search.