An investigation summarizing the benefits to gout patients if they start uric acid lowering treatment with a very low target. This reduces the time it takes to get rid of old uric acid crystals, but raises speculation that there could be negative effects if uric acid goes too low.
Fortunately, the author shows how there are no known ill-effects of very low uric acid levels, so you can set your target as low as you like.
- Reassessing serum urate targets in the management of refractory gout: can you go too low?
- Hershfield MS.
- Curr Opin Rheumatol. 2009 Mar;21(2):138-42.