Allopurinol Tablets & Kidney Disease
Allopurinol tablets are the most important weapon in any gout patient’s arsenal.
They could be more important if you also suffer from kidney disease.
Gout related research from Y P Siu and colleagues, Use of allopurinol in slowing the progression of renal disease through its ability to lower serum uric acid level,[1] investigates the use of allopurinol in patients with high uric acid levels and impaired kidney function.
They recognized that high uric acid levels (hyperuricemia) is associated strongly with the development of high blood pressure and kidney disease. As allopurinol decreases serum uric acid levels, they hypothesized that administrating allopurinol to decrease serum uric acid levels to the normal range in hyperuricemic patients with chronic kidney disease may be of benefit in decreasing blood pressure and slowing the rate of kidney disease progression.
They conducted a randomized controlled trial with 54 patients with high uric acid levels and chronic kidney disease. Half were treated with allopurinol tablets (100mg to 300mg per day), and half continued with normal treatment.
See the results of the Allopurinol Tablets & Kidney Disease study