Resveratrol Xanthine Oxidase Inhibitor

Title: Antioxidant Activity and Protective Effect on DNA Cleavage of Resveratrol. Authors: R. Acquaviva, A. Russo, A. Campisi, V. Sorrenti, C. Di Giacomo, M.L. Barcellona, M. Avitabile, A. Vanella. Published: Journal of Food Science Volume 67, Issue 1, pages 137–141, January 2002

This investigation into resveratrol as one of natures gout cures includes the following:

We have investigated the free radical scavenging capacity of resveratrol, its effects on xanthine oxidase (XO) activity, spontaneous membrane lipid oxidation, and DNA cleavage. Resveratrol showed a dose-dependent free radical scavenging activity, significant inhibition of XO activity…

Xanthine Oxidase (xanthine: oxygen oxidoreductase, E C 1.1.3.22) Activity Inhibition

Xanthine oxidase (XO) activity was evaluated spectrophotometrically by following the formation of uric acid … Different concentrations of resveratrol (50, 100, or 200 μM) were added to samples before enzyme addition and their effect on the generation of uric acid was used to calculate regression lines.

First 2 pages are shown as an image, full report is:

Resveratrol Xanthine Oxidase Inhibitor Investigation

Title:
Antioxidant Activity and Protective Effect on DNA Cleavage of Resveratrol.
Authors:
R. Acquaviva, A. Russo, A. Campisi, V. Sorrenti, C. Di Giacomo, M.L. Barcellona, M. Avitabile, A. Vanella.
Published:
Journal of Food Science Volume 67, Issue 1, pages 137–141, January 2002
Resveratrol Xanthine Oxidase Inhibitor Investigation

Related: , ,

|

GoutPal Sufferers Helped

GoutPal Sufferers Helped Chart

GoutPal consists of the main GoutPal.com reference website, and a support site, gout-pal.com, aka GoutPal Interactive.

GoutPal Interactive supports GoutPal.com by helping visitors use the website more effectively, but it has a wider role in helping gout sufferers. The selfless contributions of hundreds of fellow gout sufferers means millions of gout patients get help directly, or through better information on the main website.

At the moment, GoutPal.com is totally dependent on me, though I hope this will change in the near future. This chart clearly shows how important this is. Whilst the one-man GoutPal.com suffered the same fall as I did, the many-legged GoutPal Interactive showed continuous steady increases in the number of gout sufferers helped. A massive thank you to all GoutPal Interactive members.

GoutPal Sufferers Helped Chart

Related: ,

|

Gout Sufferers Helped

Gout Sufferers Helped (click for chart details)

Visitors to my gout websites are a good indication of how many gout sufferers find help to overcome their pain. As the biggest gout support service, I was proud to be helping people on the road to Gout Freedom at the rate of one million per year, with plans to help many, many more.

Then came my fall from a balcony, and the resulting breaks meant a break from working on the website. My own fall mirrored by a fall in visitors.

But, let us look on the bright side. There is every indication that the decline is over. I still need a few months to complete physical recovery. My gout support websites need a few months to recover to one million per year and beyond. There is every indication of forthcoming success on both fronts

Gout Sufferers Helped Chart

Related: ,

|

Tophi On Fingers

Tophi On Fingers (click for more info)

This photograph shows a right index finger and right foot that have been disfigured by gouty tophi bursting through the skin. This stage of gouty arthritis, referred to as tophaceous gout, should never occur if gout is managed properly. It happens after years of untreated high uric acid.

It is supplied by a contributor to the gout forum, who hopes it might prompt fellow gout sufferers into taking action before this happens. He also notes:

However, I am not bearing the whole blame by myself. I also blame the medical industry for not more rigorously cautioning, warning, treating me.

Tophi On Fingers Image

Related: , ,

|

Diet Gout Management Plan

Diet In A Gout Management Plan

Gout diet is crucial, but only as part of a gout management plan. This image illustrates clearly how top rheumatologists see that diet is important, but only in the context of a proper diagnosis followed by a proper treatment plan. The full chart, in Gout: Diagnosis and Management of Gouty Arthritis and Hyperuricemia, is clearly aimed at doctors, but you must also see gout diet as part of a gout treatment plan that monitors and manages your uric acid levels and all other aspects of gout.

Diet Gout Management Plan

Related: ,

|

Diet And Gout

Diet And Gout Table (click image for full size)

Table of dietary recommendations for gout management. Taken from Gout: Diagnosis and Management of Gouty Arthritis and Hyperuricemia, this diet and gout list shows how overall gout diet is much more important than individual food items.

I have included other principles in my Gout Diet Section, as their are other important food factors. Also, beverages, exercise, and other lifestyle issues must be considered. The best approach is to assess your current diet, then slowly adjust that diet, decreasing bad influences, and increasing good ones. That way, you are more likely to stick to gout diet improvements.

Diet And Gout Table

Related: , ,

|

Milk For Gout Diet

Uric Acid Percent Change After Milk

A chart comparing the 10% increase in uric acid after drinking soy milk, with the 10% decrease after drinking skim milk.

Please remember that no single individual food is important. You (or your nutritionist) should check the Gout Diet Section to fully understand the part that food and drink play in the treatment of gout)

Milk For Gout Diet Image

Related: , ,

|

The menu on the left will take you to other gouty pages.
As you move around the menu, this message will change to tell you what the page is about.